Artificial intelligence yields new antibiotic never seen before

Using a new machine-learning algorithm, MIT researchers have identified a powerful antibiotic that can kill a wide range of species of pathogenic bacteria, including some that are resistant to all known antibiotics.


The computer model, which can screen more than a hundred million chemical compounds in a matter of days, is designed to pick out potential antibiotics that kill bacteria using different mechanisms than those of existing drugs. "We wanted to develop a platform that would allow us to harness the power of artificial intelligence to usher in a new age of antibiotic drug discovery," says James Collins, the Termeer Professor of Medical Engineering and Science in MIT’s Institute for Medical Engineering and Science (IMES) and Department of Biological Engineering. "Our approach revealed this amazing molecule which is arguably one of the more powerful antibiotics that has been discovered."



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